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Altitude Changes
The CPAP machine is affected by a change in altitude, so it will operate differently at higher altitudes. At higher altitudes the air pressure decreases. With less air pressure, the CPAP machine delivers less pressure to open your airway.
Newer CPAP machines automatically compensate for altitude changes. If your CPAP doesn't have an automatic function, you may need to adjust it manually, but do this with your doctor. There are some calculations to be made for manual adjustment. In either case, discussing this with your doctor is a good idea.
At higher altitudes some machines might record a false leak detection. The lower air pressure can cause the pressure sensor in the machine to shut itself off every few seconds.